Functional Genomics - Next Generation Applications and Technologies (successor of Status Seminar Chip Technologies)

Lecture Programme

(Subject to change)

Thursday, February 3, 2011

10.30     WELCOME ADDRESS

Functional Cell Analysis

Chair: M. Hrabé de Angelis, German Research Center for Environmental Health, Munich

10.40     Metabolite sensors for single cell isolation of producing bacteria
               S. Binder, M. Bott, L. Eggeling, Forschungszentrum Jülich GmbH

11.00     Capturing and culturing of living cells on microarrays
                H. Schröder, S. Reisewitz, C.M. Niemeyer, TU Dortmund

11.20     Merging gene functional classifications and expression data
                J. Bernhardt, H. Mehlan, University of Greifswald; J. Siebourg, ETH Zurich, Basel/CH;
                S. Funke, University of Stuttgart; M. Hecker, University of Greifswald

11.40     COFFEE BREAK AND POSTER VIEWING

12.10     PLENARY LECTURE
               Chair: T. Joos, NMI, Reutlingen
               Navigating the future of personalised medicine
               A. Ferreira-Gonzalez, Virginia Commonwealth University, Richmond, VA/USA

13.00     LUNCH

DNA Analysis and Sequencing

Chair: T. Gress, Marburg University Hospital

14.10     Systems biology of mitochondrial genomes based on their statistical analysis
                M. Sadovsky, Institute of Computational Modelling of SB RAS, Krasnoyarsk/RUS;
                N. Zaitseva, Siberian Federal University, Krasnoyarsk/RUS

14.30     DNA methylation analysis for minimal-invasive breast cancer diagnostic testing
               M. Wielscher, M. Hofner, S. Schönthaler, W. Pulverer, C. Noehammer,
               A. Weinhäusel, AIT Austrian Institute of Technology GmbH, Vienna/A

14.50     CARDIoGRAM: Thirteen novel genetic loci affecting risk of coronary artery disease
                J. Erdmann, on behalf of CARDIoGRAM consortium, University of Lübeck

15.10     COFFEE BREAK AND POSTER VIEWING

DNA Sequencing

Chair: M. Buchholz, Marburg University Hospital

15.30     High-throughput sequence analysis: from technology to functional genomics
               T. Werner, Genomatix Software GmbH, Munich & University of Michigan, Ann Arbor,
               MI/USA

15.40     Next generation sequencing analysis for the characterization of transcription factors
               H. Klein, F. Kleinjung, C. Bauer, J. Schuchhardt, MicroDiscovery GmbH, Berlin

15.50     What nucleotides can tell us today: high resolution transcription profiling,
               methylation analysis and microRNAs in cancers by next generation sequencing

               P. Winter, B. Rotter, R. Horres, G. Kahl, GenXPro GmbH, Frankfurt am Main

16.00     Development of DNA capture arrays for the targeted re-sequencing of the most
               complete human exome and detection of rare variants

               G. Gradl, Eurofins MWG Operon, Ebersberg; K. May, Genomatix GmbH, Munich

16.10     High sensitive detection of KRAS mutations with hybcell compact sequencing©
               S. Eisenberger, B. Ronacher, Anagnostics Bioanalysis GmbH, St. Valentin/A

16.20     COFFEE BREAK AND POSTER VIEWING

16.50     PLENARY LECTURE
               Chair: T. Herget, Merck KGaA, Darmstadt
               Towards "Ideal Healthcare": optimised and personalised future medicine
               A.J. Brookes, University of Leicester/UK

17.40     PANEL DISCUSSION
               Genome-Wide Association Studies (GWAS)
               A.J. Brookes, J. Erdmann, T. Gress, J.D. Hoheisel, T. Meitinger,
               M. Hrabé de Angelis (moderation)

18.40     POSTER PARTY

21.00     END OF THE FIRST DAY


Friday, February 4, 2011

Proteomics I

Chair: T. Joos, NMI, Reutlingen

09.30     Some like it hot: molecular interaction studies using microscale thermophoresis
               M. Jerabek-Willemsen, C.J. Wienken, University of Munich; S. Duhr, P. Baaske,
               NanoTemper GmbH, Munich

09.50     A hand-held DNA to protein microarray translation system
               J. Burger, D. Lämmle, F. von Stetten, University of Freiburg; O. Stoevesandt,
               M.J. Taussig, The Babraham Institute, Cambridge/UK; R. Zengerle, G. Roth, University
               of Freiburg

10.10     Decyphering the antibodyome - peptide microarrays for routine high throughput
               seroanalytics

               C.J.M. Grötzinger, Charité - Universitätsmedizin Berlin; H. Andresen, Fraunhofer IBT,
               Potsdam; J.L. Körner, Charité - Universitätsmedizin Berlin; O.J. Kreuzer,
               peptides&elephants GmbH, Potsdam; J.M. Hollidt, in.vent Diagnostica GmbH,
               Hennigsdorf

10.30     Molecular profiling of protein networks in formalin-fixed and paraffin-embedded
               cancer tissues

               D. Berg, K.-F. Becker, Technische Universität München

10.50     POSTER AWARDS

11.00     COFFEE BREAK AND POSTER VIEWING

Proteomics II

Chair: T. Herget, Merck KGaA, Darmstadt

11.30     Antibody microarray-based proteomic profiling of 24 pancreatic cancer cell lines
               revealed new leads characteristic to the disease, its degree of differentiation,
               source of cells, and the metastatic potential

               M.S.S. Alhamdani, S. Mustafa, C. Schröder, M. Youns, A. Bauer, J.D. Hoheisel, DKFZ,
               Heidelberg

11.50     Kinetic profiling of antigen-antibody interactions
               K. Köhler, MPI for Molecular Genetics, Berlin; M. Or-Guil, Humboldt-Universität zu Berlin;
               N. Babel, Charité University Medicine Berlin; H. Seitz, MPI for Molecular Genetics, Berlin

12.10     Analysis of signalling networks in drug discovery: combining tumour spheroid and
               protein microarray technology in drug efficacy screening

               Y. Heubach, E. Breitinger, B. Gierke, T. Knorpp, A.K. Hummel, NMI Natural and Medical
               Sciences Institute at the University of Tübingen, Reutlingen; B. Mayer, SpheroTec
               GmbH, Martinsried; S. Strobl, 4SC AG, Martinsried; M. Pawlak, M.F. Templin, NMI
               Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen

12.30     CLOSING REMARKS

12.40     LUNCH AND END OF THE CONFERENCE


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