Functional Genomics - Next Generation Applications and Technologies (successor of Status Seminar Chip Technologies)

Poster Programme

P01     Chip-based antibody-array for single-molecule sensitive detection of Tuberculosis
            antigen

            R. Schmidt, German Cancer Research Center, Heidelberg; J. Jacak, Johannes Kepler
            University Linz/A; C. Schirwitz, German Cancer Research Center, Heidelberg; V. Stadler,
            PEPperPRINT GmbH, Heidelberg; G. Michel, Foundation for Innovative New Diagnostics
            (FIND), Geneva/CH; N. Marmé, University of Heidelberg; G.J. Schütz, Johannes Kepler
             University Linz/A; J.D. Hoheisel, J.P. Knemeyer, German Cancer Research Center,
             Heidelberg

P02     Solving the mystery of the amino linker: understanding immobilization of molecules on
            microarray surfaces

            J. Sobek, R. Schlapbach, Functional Genomics Center Zurich/CH; W. Weigel, Humboldt
            University of Berlin

P03     Pseudomonas putida KT2440 genome update by cDNA sequencing and microarray
            transcriptomics

            S. Frank, J. Klockgether, Hannover Medical School; P. Hagendorf, R. Geffers, Helmholtz
            Centre for Infection Research, Braunschweig; U. Schöck, T. Pohl, GATC Biotech AG,
            Konstanz; C. Davenport, B. Tümmler, Hannover Medical School

P04     Extreme properties of genomes and their information capacity
            A.A. Koval, V.M. Lougovoy, Siberian Federal University, Krasnoyarsk/RUS; M.G. Sadovsky,
            Institute of Computational Modelling of SB RAS, Krasnoyarsk/RUS

P05      Highly parallel characterization of gene function
             M. Boettcher, J. Fredebohm, J. Wolf, J.D. Hoheisel, German Cancer Research Center,
             Heidelberg

P06      Combinatorial symmetry in genomes
             E. Temlyakova, V. Lougovoy, Siberian Federal University, Krasnoyarsk/RUS;
             M. Sadovsky, Institute of Computational Modelling SB RAS, Krasnoyarsk/RUS

P07      Deep sequencing of mitochondrial genomes and transcriptomes
              J. Altmüller, C. Becker, University of Cologne; G. Zsurka, University of Bonn;
              R. Bundschuh, Ohio State University, Columbus, OH/USA; W. Kunz, University of Bonn;
              J. Gott, Case Western Reserve University, Cleveland, OH/USA; P. Nürnberg, University
              of Cologne

P08     Passage: a fast and efficient sequence clustering method for RNA-seq data without a
            reference genome

            F. Battke, Center for Bioinformatics, Tuebingen; S. Körner, S. Hüttner, Hölle & Hüttner AG,
            Tuebingen; K. Sohn, Fraunhofer IGB, Stuttgart; K. Nieselt, Center for Bioinformatics,
            Tuebingen

P09     Sol-gel system broad utility in binding assays future: from target discovery to drug
            development

            M. Jo, S. Lee, H. Andrade, B.-D. Han, PCL Inc., Suwon/ROK; W. Weigel, J. Hempel,
            Scienion AG, Berlin

P10    Identification of new causative genes in patients with adenomatous polyposis by CNV
           analysis

            S. Horpaopan, S. Vogt, I. Spier, M.M. Nöthen, P. Hoffmann, S. Aretz, University of Bonn

P11    CMOS polysaccharide microarrays for fast vaccination control
            J. Baader, H. Klapproth, S. Bednar, T. Brandstetter, J. Rühe, University of Freiburg;
            H. Eibel, H.-H. Peter, University Hospital Freiburg; M. Lehmann, I. Freund, Micronas
            GmbH, Freiburg

P12    Microarray-based amplification and detection of microRNAs (miRNAs) by NASBA
            (nucleic acid sequence based amplification)

            U. Riehle, University Hospital Freiburg; A. Mader, T. Brandstetter, J. Rühe, University of
            Freiburg; A. zur Hausen, E. Stickeler, University of Freiburg

P13    Towards quantitative microarray-based NASBA: real-time kinetic recording by
            competitive displacement

           A. Hoppmann, A. Mader, T. Brandstetter, J. Rühe, University of Freiburg

P14    Quantitative protein biomarker analysis in formalin fixed tissues - searching for
            industrial collaboration

            K. Malinowsky, C. Wolff, K.-F. Becker, Technische Universität München

P15    Dual-colour protein analysis on complex antibody microarrays for the profiling of
           cancer proteomes

           C. Schröder, A. Jacob, M.S.S. Alhamdani, A. Nieters, S. Rüffer, A. Bauer, K. Fellenberg,
           J.D. Hoheisel, German Cancer Research Center, Heidelberg

P16    Inferring gene-regulatory networks via correlation
           M. Maucher, Ulm University Hospital; B. Kracher, M. Kühl, University of Ulm; M. Buchholz,
           T. Gress, Marburg University Hospital; H.A. Kestler, University of Ulm

P17    Protein quantification using reverse phase protein microarrays
           R. Wild, H. Seitz, MPI for Molecular Genetics, Berlin

P18    Tumor master stem cells and their rapid genetic modification: the incentive to further
           development of a new generation in chip-technology

           N. Klehr, L.H. Bauer, Dr. Klehr Institut für Immunologie und Zellbiologie, Munich; S. Sowa,
           J. Setter, Haemotec GmbH, Grünwald

P19    Parallelized functional characterization of pancreatic cancer candidate genes on
           reverse transfection cell microarrays

           S. Melchisedech, T. Honstein, R. Kreider, T.M. Gress, M. Buchholz, University of Marburg

P20    Differentiation of multiple histological subtypes of pancreatico-biliary tumors by
           molecular analysis of clinical specimens

           T.M. Gress, University of Marburg; H.A. Kestler, L. Lausser, University of Ulm; B. Sipos,
           University Hospital Tuebingen; C. Michalski, Technical University Munich; N. Giese,
           J. Werner, University of Heidelberg; A. Scarpa, University of Verona/I; M. Buchholz,
           University of Marburg

P21    Expression profiling of marine microbial communities with 454 pyrosequencing
           A. Klindworth, C. Klockow, E. Karamehmedovic, B. Öztürk, H. Teeling, J. Waldmann,
           A. Mann, T. Hammer, F.O. Glöckner, MPI for Marine Microbiology, Bremen

P22    Analyzing splicing patterns by high-resolution RNA-Seq expression profiles
           R. Deenen, T. Wachtmeister, Heinrich Heine University Düsseldorf; H. Schaal, M. Widera,
           University Hospital Düsseldorf; K. Köhrer, Heinrich Heine University Düsseldorf

P23    Cross array platform miRNA profiling during cardiomyocyte-specific differentiation of
           ESCs

           L. Gan, RWTH Aachen University; S. Schwengberg, Axiogenesis AG, Cologne;
           B. Denecke, RWTH Aachen University

P24    Unbiased quantitative pyrosequencing assay reveals concurrent epigenetic silencing
           of Wnt signaling inhibitors in B-cell chronic lymphocytic leukemia

           E.A. Moskalev, German Cancer Research Center, Heidelberg; I.A. Vorobjev,
           A.A. Gladkikh, National Hematology Research Center, Moscow/RUS; M.G. Zavgorodnij,
           Voronezh State University/RUS; S.P. Majorova, Voronezh State Technical University/RUS;
           A. Stephan, M. Schrenk, I. Bure, P. Jandaghi, J.D. Hoheisel, German Cancer Research
           Center, Heidelberg

P25    Subgenome fractionation of up to 12 samples using only one microarray for targeted
           HT-sequencing

           S. Kelkenberg-Schade, B. Haldemann, T. Fries, N. Wermke, German Cancer Research
           Center, Heidelberg; A. Pfeufer, Helmholtz Center Munich; B. Meder, University of
           Heidelberg; S. Wolf, B. Korn, M. Scharfenberger-Schmeer, German Cancer Research
           Center, Heidelberg

P26    Simultaneous methyl binding domain (MBD) protein based DNA isolation and
           serum-autoantibody testing from human blood serum

           M. Wielscher, M. Hofner, C. Noehammer, A. Weinhäusel, AIT Austrian Institute of
           Technology GmbH, Vienna/A

P27    CpG methylation microarray elucidates DNA methylation changes in cell cultures
            A. Weinhaeusel, AIT Austrian Institute of Technology GmbH, Vienna/A; W. Mikulits,
            Medical University of Vienna/A; M. Hofner, W. Pulverer, R. Pichler, K. Vierlinger,
            C. Noehammer, AIT Austrian Institute of Technology GmbH, Vienna/A

P28    Optimization of fluorescence signals on rolling circle amplification-enhanced
           microarrays

           L. Linck, BAM Federal Institute for Materials Research and Testing, Berlin; E. Reiß,
           F. Bier, Fraunhofer IBMT, Potsdam; J. Sobek, Functional Genomics Center Zurich/CH;
           U. Resch-Genger, BAM Federal Institute for Materials Research and Testing, Berlin

P29    Aptamers enable the differentiation of indoor moulds
           C. Reinemann, J.-F. Ducroz, A. Müller, B. Strehlitz, Helmholtz Centre for Environmental
           Research GmbH - UFZ, Leipzig

P30    CountBases - a bioinformatic platform for next-generation transcriptome analyses
           S. Lorenz, C. Grumaz, S. Rupp, K. Sohn, Fraunhofer IGB, Stuttgart

P31    Aptamer-microarrays: reverse and sandwich formate
           M. Lübbecke, J.-G. Walter, F. Stahl, T. Scheper, Leibniz Universität Hannover

P32    Screening of aptamers for analytical applications via microarrays
           J.-G. Walter, M. Lübbecke, G. Zhu, F. Stahl, T. Scheper, Leibniz Universität Hannover

P33    Integrated genomic profiling for improved sub-classification of aggressive b-cell
           lymphoma based on a universal array platform

           S. Weishaupt, University of Stuttgart; J.D. Hoheisel, German Cancer Research Center,
           Heidelberg; C. Thorns, H. Merz, University of Schleswig-Holstein, Lübeck; N.C. Hauser,
           K. Lemuth, S. Rupp, Fraunhofer IGB, Stuttgart

P34    A step towards an improved diagnosis of prostate cancer in patients with elevated
           PSA levels

           S. Rimmele, NMI Natural and Medical Sciences Institute at the University of Tuebingen,
           Reutlingen; A. Lüking, A. Höpfner, P. Schulz-Knappe, Protagen AG, Dortmund; T. Joos,
           N. Schneiderhan-Marra, NMI Natural and Medical Sciences Institute at the University of
           Tuebingen, Reutlingen

P35    A polymer hydrogel immobilization technique for attachment of DNA molecules in
           microfluidic structures

           F. Scherag, University of Freiburg; C. Carstens, Laborpraxis Elbracht, Naumburg;
           N. Hlawatsch, microfluidic ChipShop GmbH, Jena; T. Brandstetter, J. Rühe, University of
           Freiburg

P36    XworX - next generation data analysis framework
           A. Kriegner, A. Yildiz, E. Dilaveroglu, I. Visne, K. Vierlinger, A. Weinhaeusel,
           C. Noehammer, AIT Austrian Institute of Technology GmbH, Vienna/A

P37    Stability analysis of marker selection techniques for high-dimensional biological data
           L. Lausser, University Hospital Ulm; C. Müssel, University of Ulm; M. Markus, University
           Hospital Ulm; H.A. Kestler, University of Ulm & University Hospital Ulm

P38    Tiling array analysis of the small RNA fraction of the microbial amino acid producer
           Corynebacterium glutamicum

           J. Pahlke, N. Dobler, Forschungszentrum Jülich GmbH; C. Hafemeister, MPI for
           Molecular Genetics, Berlin; A. Schliep, University of New Jersey, Rutgers, NJ/USA; M. Bott,
           T. Polen, Forschungszentrum Jülich GmbH

P39    On chip PCR products for in situ protein expression
           S. Syafrizayanti, C. Di, M. Fugazza, J.D. Hoheisel, German Cancer Research Center,
           Heidelberg

P40    Functional genomics for regenerative medicine: optimization of stem cells in live cell
           chips

           C. Maercker, Mannheim University of Applied Sciences; K. Bieback, I. Brinkmann,
           University of Heidelberg, Mannheim; D. Breitkreutz, M. Angstmann, Mannheim University
           of Applied Sciences

P41    Functional 3D-surfaces for "everyone"
           C. Heise, U. Schedler, PolyAn GmbH, Berlin

P42   Characterization of novel epi-mutations in breast cancer with respect to their potential
           contribution to an epigenetic field defect

           Y. Riazalhosseini, A. Moghaddas Gholami, German Cancer Research Center, Heidelberg;
           M. Malekpour, Tehran University of Medical Sciences/IR; S. Kumar Botla, A. Jahangiri
           Babadi, German Cancer Research Center, Heidelberg; V. Bubnov, Odessa State Medical
           University/UA; H. Najmabadi, University of Social Welfare and Rehabilitation Sciences,
           Tehran/IR; J.D. Hoheisel, German Cancer Research Center, Heidelberg

P43    Pathogenicity related genes among the Streptomyces species causing potato scab
           diseases group

           G. Khodakaramian, Bu - Ali Sina University, Hamedan/IR

P44    Segmentation of tumor tissue in gray medical images using watershed
           transformation method

           S.D.S. Al-Shaikhli, A.A.M. Bahrani, University of Baghdad/IRQ

LMP01 Lack of beta1 integrin results in hemivertebrae development in mice
             S. Guo, S. Wynn, T. Au, D. Chan, The University of Hong Kong/PRC; A. Aszodi, R. Fassler,
             MPI of Biochemistry, Martinsried; K. Cheah, The University of Hong Kong/PRC

LMP02 Large scale RNAi screen to identify synthetic lethal partners of DNA-PKCS in
              pancreatic cancer

             J. Fredebohm, M. Böttcher, J.D. Hoheisel, German Cancer Research Center, Heidelberg

LMP03 Highly sensitive detection of microRNA and mRNA from FFPE tissue and blood
              samples by expression microarray

              H. Sudo, S. Takizawa, Y. Ueda, T. Kuroda, M. Ichikawa, O. Nomura, H. Akiyama,
              H. Nobumasa, Toray Industries, Inc., Kanagawa/J

LMP04 Robust and reproducible automated tissue homogenization
             C. Poggel, T. Adams, A. Langhammer, A. Bosio, Miltenyi Biotec GmbH, Bergisch
             Gladbach

LMP05 Lab-on-chip based mulitparameter analysis for point-of-care testing
             E. Ehrentreich-Förster, Fraunhofer IBMT, Potsdam; S. Schumacher, K. Wunderlich,
             University of Potsdam; D. Michel, F. Bier, Fraunhofer IBMT, Potsdam

LMP06 In situ protein tagging for proteome analysis in mouse embryonic stem cells
             F. Schnütgen, F. Ehrmann, University of Frankfurt Medical School; I. Poser, MPI for
             Molecular Cell Biology and Genetics, Dresden; N. Hubner, MPI of Biochemistry,
             Martinsried; T. Floss, W. Wurst, Helmholtz Center München, Neuherberg; T. Hyman,
             MPI for Molecular Cell Biology and Genetics, Dresden; M. Mann, MPI of Biochemistry,
             Martinsried; H. von Melchner, University of Frankfurt Medical School

LMP07 Protease profiling with reporter peptides for tumor diagnosis
              A. Jacob, M. Dauber, German Cancer Research Center & Peps4LS, Heidelberg;
             J.D. Hoheisel, German Cancer Research Center, Heidelberg; R. Hofheinz, D. Yepes,
             V. Costina, M. Neumaier, P. Findeisen, University Hospital Mannheim

LMP08 Epigenetically deregulated microRNA-375 enhances Estrogen Receptor α activity in
             breast cancer

             P. de Souza Rocha Simonini, A. Breiling, N. Gupta, German Cancer Research Center,
             Heidelberg; M. Malekpour, Tehran University of Medical Sciences/IR; M. Youns, German
             Cancer Research Center, Heidelberg; R. Omranipour, Tehran University of Medical
             Sciences/IR; F. Malekpour, Shahid Beheshti University of Medical Sciences, Tehran/IR;
             S. Volinia, University of Ferrara/I; C.M. Croce, The Ohio State University, Columbus,
             OH/USA; H. Najmabadi, University of Social Welfare and Rehabilitation, Tehran/IR;
             S. Diederichs, Ö. Sahin, D. Mayer, F. Lyko, J.D. Hoheisel, Y. Riazalhosseini, German
             Cancer Research Center, Heidelberg

LMP09 Production of protein microarrays by cell-free in situ expression
              M. Fugazza, J.D. Hoheisel, German Cancer Research Centre, Heidelberg



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